The GTPB runs face-to-face Bioinformatics Training Courses regularly at the Instituto Gulbenkian de Ciência since 1999. Up to now, more than 4500 course participants have acquired practical skills that they can use with a high degree independence. The Programme consists in a series of short, intensive hands-on courses delivered and fully documented in English. The design of the courses is based on sets of carefully chosen exercises, flanked by short lectures and participative interaction sessions.