GTO is a toolkit to unify pipelines in genomic and proteomic research. GTO is a toolkit for genomics and proteomics, namely for FASTQ, FASTA and SEQ formats, with many complementary tools. The toolkit is for Unix-based systems, built for ultra-fast computations. GTO supports pipes for easy integration with the sub-programs belonging to GTO as well as external tools. GTO works as LEGOs, since it allows the construction of multiple pipelines with many combinations

 EAGLE is an alignment-free method and associated program to compute relative absent words (RAW) in genomic sequences using a reference sequence